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From the Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, HadassahHebrew University Hospital, Jerusalem, Israel.
Address correspondence and reprint requests to Dr. Tamir Ben-Hur, Department of Neurology, HadassahHebrew University Hospital, P.O. Box 12000, Ein Kerem, Jerusalem, Israel; e-mail: tamir{at}hadassah.org.il
Six patients who fulfilled strictly defined criteria for migrainous cerebral infarction and in whom other causes of stroke were ruled out were observed. All had a long-standing history of migraine with aura. In most, stroke was mild with good recovery and no recurrence. Headache frequency and severity decreased after the stroke. It is hypothesized that the improvement in migraine may be due to reduced nociceptive transmission as result of loss in vasoreactivity of the affected cerebral blood vessel.
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