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From the Department of Neuroscience (Dr. L. Grimaldi), Azienda Unita Sanitaria Locale 2, Caltanissetta; Institute of Neuropsychiatry (Drs. Salemi and Savettieri), University of Palermo; Neurology Unit (Drs. G. Grimaldi and Rizzo), Umberto I Hospital, Enna; Neurology Unit (Dr. Marziolo), SantElia Hospital, Caltanissetta; Sicilian Rehabilitation Consortium (Dr. Lo Presti), Enna; and Neurology Unit (Dr. Maimone), Garibaldi Hospital, Catania, Italy.
Address correspondence and reprint request to Dr. G. Savettieri, Institute of Neuropsychiatry, University of Palermo, Via Gaetano La Loggia 1-90129 Palermo, Italy; e-mail: gsavetti{at}tin.it
Twenty years after a first survey, a follow-up study was performed on the prevalence of MS in Enna (Sicily), southern Italy. The prevalence of definite MS rose from 53 to 120.2 per 100,000 population. The incidence of definite MS for the period 1986 to 1995 was 5.7 per 100,000 per year. The innermost part of Sicily shows an elevated prevalence of MS, second only to Sardinia in the Mediterranean area.
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