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The efficacy of epidural blood patch in spontaneous CSF leaks

From Departments of Radiology (Dr. Sencokova), Neurology (Dr. Mokri), and Section of Biostatistics, Department of Health Sciences Research (Dr. McClelland), Mayo Clinic and Mayo Foundation; Rochester, MN.

Address correspondence and reprint requests to Dr. Bahram Mokri, Mayo Clinic, Department of Neurology, 200 First Street SW, Rochester, MN 55905.

Of 25 consecutive patients with spontaneous CSF leaks treated with epidural blood patch (EBP), nine patients (36%) responded well to the first EBP. Of 15 patients who received a second EBP, five became asymptomatic (33%). Of eight patients who received three or more EBP (mean 4), four patients (50%) responded well.

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