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Neurology 2001;57:2133-2135
© 2001 American Academy of Neurology


Brief Communications

Menstrual cycle interval and ovulation in women with localization-related epilepsy

Andrew G. Herzog, MD, MSc and Mark N. Friedman, DO

From the Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA.

Address correspondence and reprint requests to Dr. Andrew G. Herzog, Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215; e-mail: aherzog{at}caregroup.harvard.edu

Article abstract—— In an investigation of 100 women with localization-related epilepsy, anovulatory cycles were significantly greater in proportion in women with 21–25 or 33–35 day cycles (Group B) and in women with less than 21 or more than 35 day cycles (Group C) than in women with normal 26–32 day intervals (Group A). Groups B and C also had significantly higher estradiol/progesterone ratios than Group A. Nevertheless, almost one-half (46.2%) of the anovulatory cycles occurred in women with normal 26–32 day cycles.




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