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From the Departments of Neurology (Drs. Fujii and Yamaguchi) and Pathology (Dr. Nakanishi), Iizuka Hospital, Iizuka; and Department of Neuropathology (Drs. Furuta and Iwaki), Neurological Institute, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan.
Address correspondence and reprint requests to Dr. Naoki Fujii, Department of Neurology, National Chikugo Hospital, Kurakazu 515, Chikugo 833-0054, Japan; e-mail: fujii{at}tikugo.hosp.go.jp
The authors report an autopsied patient with limbic encephalitis and recurrent thymoma. The immunohistochemical study showed selective depositions of immunoglobulin G on the neurons in the limbic system and the tumor cells of the recurrent thymoma. The immunoblotting study detected two types of antibodies that react with the human brain, rat brain, and rat thymus.
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K. Hammoud, G. Kandimala, W. Warnack, and S. Vernino Multifocal Paraneoplastic Cortical Encephalitis Associated With Myasthenia Gravis and Thymoma Arch Neurol, November 1, 2009; 66(11): 1407 - 1409. [Abstract] [Full Text] [PDF] |
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