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False lateralization by subdural electrodes in two patients with temporal lobe epilepsy

From the Departments of Neurology (Drs. Alsaadi, Laxer, Marks, and Garcia) and Neurological Surgery (Dr. Barabaro), University of California, San Francisco, CA.

Address correspondence and reprint requests to Dr. Taoufik Alsaadi, Department of Neurology, 4860 Y Street, Suite 3700, University of California, Davis, Sacramento, CA 95817; e-mail: taoufik.alsaadi{at}ucdmc.ucdavis.edu

The authors present two patients with medically refractory partial seizures who had invasive recordings with stereotactic depth EEG (SEEG) and subdural electrodes (SDE) as part of their presurgical workup. SDE recordings were falsely lateralizing in both of these patients with pathologically proven mesial temporal sclerosis. In temporal lobe epilepsy, SEEG electrodes should be considered when presurgical studies are discordant.

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