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Neurology 2001;57:716-718
© 2001 American Academy of Neurology
Brief Communications

Primary central nervous system T-cell lymphoma

Johanna M. M. Gijtenbeek, MD;, Marc K. Rosenblum, MD; and Lisa M. DeAngelis, MD

From the Departments of Neurology (Drs. Gitjenbeek and DeAngelis) and Pathology (Dr. Rosenblum), Memorial Sloan–Kettering Cancer Center, New York, NY.

Address correspondence and reprint requests to Dr. Lisa M. DeAngelis, Department of Neurology, Memorial Sloan–Kettering Cancer Center, 1275 York Avenue, New York, NY 10021; e-mail: deangell{at}mskcc.org

Most primary CNS lymphomas (PCNSL) are B-cell neoplasms; T-cell lymphomas are quite rare. The authors report two young patients with T-cell PCNSL who had a complete response to chemo- and radiotherapy but developed recurrent disease and died 11 and 13 months from diagnosis. The prognosis of T-cell PCNSL may be worse than that of comparable B-cell tumors.




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