| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
From the Department of Neurology (Dr. Aksamit) and the Department of Laboratory Medicine and Pathology (Dr. Homburger and C. Pressier), Mayo Clinic, Rochester, MN.
Address correspondence and reprint requests to Dr. Allen J. Aksamit, Jr., Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.
CSF 14-3-3 and neuron-specific enolase (NSE) proteins were quantitated from patients who had Creutzfeldt–Jakob disease (CJD) or other rapidly dementing disorders initially considered to be CJD. Thirty-one patients were diagnosed as having CJD among 152 studied. CSF 14-3-3 values more than 8 ng/mL correlated with CJD. CSF NSE values less than 30 ng/mL and 14-3-3 values less than 8 ng/mL made a diagnosis of CJD unlikely, but did not exclude it.
This article has been cited by other articles:
|
|
 |
|
  P. Brown Transmissible spongiform encephalopathy in the 21st century: Neuroscience for the clinical neurologist Neurology, February 26, 2008; 70(9): 713 - 722. [Full Text] [PDF]
|
|
|
|
 |
|
 B. Yutzy, E. Holznagel, C. Coulibaly, A. Stuke, U. Hahmann, J.-P. Deslys, G. Hunsmann, and J. Lower Time-course studies of 14-3-3 protein isoforms in cerebrospinal fluid and brain of primates after oral or intracerebral infection with bovine spongiform encephalopathy agent J. Gen. Virol., December 1, 2007; 88(12): 3469 - 3478. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Noguchi-Shinohara, T. Hamaguchi, T. Kitamoto, T. Sato, Y. Nakamura, H. Mizusawa, and M. Yamada Clinical features and diagnosis of dura mater graft-associated Creutzfeldt-Jakob disease Neurology, July 24, 2007; 69(4): 360 - 367. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Sanchez-Juan, A. Green, A. Ladogana, N. Cuadrado-Corrales, R. Saanchez-Valle, E. Mitrovaa, K. Stoeck, T. Sklaviadis, J. Kulczycki, K. Hess, et al. CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology, August 22, 2006; 67(4): 637 - 643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. A. Wall, T. A. Rummans, A. J. Aksamit, L. E. Krahn, and V. S. Pankratz Psychiatric Manifestations of Creutzfeldt-Jakob Disease: A 25-Year Analysis J Neuropsychiatry Clin Neurosci, November 1, 2005; 17(4): 489 - 495. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B R J Van Everbroeck, J Boons, and P Cras 14-3-3 {gamma}-isoform detection distinguishes sporadic Creutzfeldt-Jakob disease from other dementias J. Neurol. Neurosurg. Psychiatry, January 1, 2005; 76(1): 100 - 102. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Castellani, M. Colucci, Z. Xie, W. Zou, C. Li, P. Parchi, S. Capellari, M. Pastore, M. H. Rahbar, S. G. Chen, et al. Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease Neurology, August 10, 2004; 63(3): 436 - 442. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Jin, Y. Shiga, S. Shibuya, K. Chida, Y. Sato, H. Konno, K. Doh-ura, T. Kitamoto, and Y. Itoyama Clinical features of Creutzfeldt-Jakob disease with V180I mutation Neurology, February 10, 2004; 62(3): 502 - 505. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. S. Knopman, B. F. Boeve, and R. C. Petersen Essentials of the Proper Diagnoses of Mild Cognitive Impairment, Dementia, and Major Subtypes of Dementia Mayo Clin. Proc., October 1, 2003; 78(10): 1290 - 1308. [Abstract] [PDF]
|
|
|
|
 |
|
 A. J. Aksamit Cerebrospinal Fluid 14-3-3 Protein: Variability of Sporadic Creutzfeldt-Jakob Disease, Laboratory Standards, and Quantitation Arch Neurol, June 1, 2003; 60(6): 803 - 804. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
