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Neurology 2001;57:1486-1488
© 2001 American Academy of Neurology
Brief Communications

Gliomas arising in organ transplant recipients: An unrecognized complication of transplantation?

D. Schiff, MD, B. O’Neill, MD, E. Wijdicks, MD, J. H. Antin, MD and P. Y. Wen, MD

From the Department of Neurological Surgery (Dr. Schiff), University of Pittsburgh Medical Center, PA; Department of Neurology (Drs. O’Neill and Widjicks), Mayo Clinic, Rochester, MN; and Center for Neuro-Oncology (Dr. Wen), Dana Farber Cancer Institute (Dr. Antin), Boston, MA.

Address correspondence and reprint requests to Dr. D. Schiff, Neuro-Oncology Program, University of Pittsburgh Medical Center, 3471 Fifth Ave., Kaufmann Building, Suite 802, Pittsburgh, PA 15213; e-mail: schiffd{at}msx.upmc.edu

Reported are six cases of glioma, diagnosed in the last 10 years, arising in organ transplant recipients. Five transplant recipients developed glioblastoma, and one developed oligodendroglioma. None had other risk factors for glioma. Gliomas must be considered in the differential diagnosis of space-occupying lesions in transplant recipients. Although these cases may represent coincidence, the putative HIV–glioma association suggests a pathogenetic link to immunosuppression.




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W.Y. Au, K.N. Hung, F. Loong, and S.K. Ma
Patients Presenting With CNS Lesions: CASE 3. SEQUENTIAL MYELOPROLIFERATIVE DISEASE AND GLIOBLASTOMA MULTIFORME IN A RENAL TRANSPLANT RECIPIENT
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