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Right arrow Status epilepticus
Neurology 2002;58:139-142
© 2002 American Academy of Neurology


Brief Communications

Predictors of functional disability and mortality after status epilepticus

J. Claassen, MD, J. K. Lokin, MD, B.-F. M. Fitzsimmons, MD, F. A. Mendelsohn, BA and S. A. Mayer, MD

From the Department of Neurology, Division of Critical Care Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY.

Address correspondence and reprint requests to Dr. Stephan A. Mayer, Division of Critical Care Neurology, 710 West 168th Street, Unit 39, New York, NY 10032; e-mail: sam14{at}columbia.edu

The authors identified predictors of functional disability and mortality after status epilepticus in a multivariate analysis of 83 episodes in 74 patients. Twenty-one percent (14/85) of episodes were fatal. Increased age (OR = 1.1; 95% CI, 1.0 to 1.1) and acute symptomatic seizures (OR = 6.0; 95% CI, 1.2 to 30.3) were predictors of mortality. Functional outcome at discharge deteriorated in 23% (16/69) of nonfatal episodes. Increased length of hospitalization (OR = 1.04; 95% CI, 1.0 to 1.1) and acute symptomatic seizures (OR = 3.9; 95% CI, 1.0 to 14.7) were predictors of functional disability.




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