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From the Departments of Neurology (Drs. Hong, Turner, and Foster), Radiology (Dr. Shah), and Psychiatry (Dr. Adams), University of Michigan, School of Medicine, Ann Arbor, MI.
Address correspondence and reprint requests to Dr. Norman L. Foster, Department of Neurology, University of Michigan, 1920 Taubman, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0316; e-mail: nlfoster{at}umich.edu
Spontaneous intracranial hypotension (SIH) causes postural headache and neurologic symptoms owing to traction and brain compression. A 66-year-old man with chronic headache and progressive personality and behavioral changes typical of frontotemporal dementia was examined. He had MRI findings of SIH with low CSF pressure. His headache, dementia, and imaging abnormalities abated after treatment with prednisone. SIH can cause reversible frontotemporal dementia, and should be considered when dementia and behavioral changes are accompanied by headache.
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