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Neurology 2002;58:1288-1290
© 2002 American Academy of Neurology
Brief Communications

Improved executive functioning following repetitive transcranial magnetic stimulation

D. J. Moser, PhD, R. E. Jorge, MD, F. Manes, MD, S. Paradiso, MD, M. L. Benjamin, BS and R. G. Robinson, MD

From the Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA.

Address correspondence and reprint requests to Dr. David J. Moser, Department of Psychiatry JPP 2880, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52240; e-mail: David-Moser{at}uiowa.edu

The cognitive effects of active and sham repetitive transcranial magnetic stimulation (rTMS) were examined in 19 middle-aged and elderly patients with refractory depression. Patients received either active (n = 9) or sham (n = 10) rTMS targeted at the anterior portion of the left middle frontal gyrus. Patients in the active rTMS group improved significantly on a test of cognitive flexibility and conceptual tracking (Trail Making Test–B).




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