HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) CME: Take the course for this article: Volume 59, Number 10, November 26, 2002 Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Eliashiv, D.S. Articles by Engel, J. Search for Related Content PubMed PubMed Citation Articles by Eliashiv, D.S. Articles by Engel, J., Jr. Related Collections All Imaging Magnetic Source Imaging (MSI) All Epilepsy/Seizures Cortical localization Partial seizures

Ictal magnetic source imaging as a localizing tool in partial epilepsy

From the Departments of Neurology (Drs. Eliashiv and Engel) and Neurosurgery (Dr. Fried), University of California Los Angeles; Division of Neurology (Dr. Eliashiv), Cedars Sinai Medical Center, Los Angeles, CA; Department of Neurology (Dr. Elsas), Oregon Health and Sciences University, Portland; and Magnetic Source Imaging (Dr. Squires), Scripps Clinic, San Diego, CA.

Address correspondence and reprint requests to Dr. Dawn S. Eliashiv, Division of Neurology, Cedars Sinai Medical Center, 8700 Beverly Blvd., Rm. 4127, Los Angeles, CA 90048; e-mail: eliashivd{at}cshs.org

Objective: To determine the feasibility and usefulness of ictal magnetoencephalography (MEG) recordings in the presurgical evaluation of patients with epilepsy.

Methods: Twenty patients with frequent or predictable seizures were studied with the intent to capture seizures using a large array single-probe 37-channel or dual-probe 74-channel biomagnetometer.

Results: Successful ictal MEG recordings were made in 6 of 20 patients with neocortical epilepsy. In one other patient, a seizure was captured but movement artifact made MEG recordings impossible. As determined by invasive EEG recording and postsurgical outcome, ictal MEG provided localizing information that was superior to interictal MEG in three of the six patients. Localization of ictal onset by MEG was at least equivalent to invasive EEG in five of the six patients, and was superior in two patients as determined by postsurgical outcome.

Conclusion: Larger studies are necessary to confirm that ictal MEG recordings in patients with frequent or easily provoked neocortical seizures can contribute localizing information equivalent or superior to invasive EEG recording.

This article has been cited by other articles:

				Z. Agirre-Arrizubieta, G. J. M. Huiskamp, C. H. Ferrier, A. C. van Huffelen, and F. S. S. Leijten Interictal magnetoencephalography and the irritative zone in the electrocorticogram Brain, November 1, 2009; 132(11): 3060 - 3071. [Abstract] [Full Text] [PDF]

				I. S. Mohamed, H. Otsubo, K. Imai, M. Shroff, R. Sharma, S. H. Chuang, E. Donner, J. Drake, and O. C. Snead III Surgical Treatment for Acute Symptomatic Refractory Status Epilepticus: A Case Report J Child Neurol, April 1, 2007; 22(4): 435 - 439. [Abstract] [PDF]

				E. Pataraia, P.G. Simos, E.M. Castillo, R.L. Billingsley, S. Sarkari, J.W. Wheless, V. Maggio, W. Maggio, J.E. Baumgartner, P.R. Swank, et al. Does magnetoencephalography add to scalp video-EEG as a diagnostic tool in epilepsy surgery? Neurology, March 23, 2004; 62(6): 943 - 948. [Abstract] [Full Text] [PDF]

				N Tanaka, K Kamada, and F Takeuchi Ictal magnetoencephalographic study in a patient with ring 20 syndrome J. Neurol. Neurosurg. Psychiatry, March 1, 2004; 75(3): 488 - 490. [Abstract] [Full Text] [PDF]