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Olfactory dysfunction in essential tremor

A deficit unrelated to disease duration or severity

From the Gertrude H. Sergievsky Center (Dr. Louis, E.C. Jurewicz, and D. Watner) and the Department of Neurology (Drs. Louis and Bromley), College of Physicians and Surgeons, Columbia University, New York, NY.

Address correspondence and reprint requests to Dr. Elan Louis, Unit 198, Neurological Institute, 710 West 168th Street, New York, NY 10032; e-mail: EDL2{at}columbia.edu

Because olfactory dysfunction is a feature of neurodegenerative diseases, the authors hypothesized that it would be present in essential tremor. Thirty-seven cases and control subjects underwent the University of Pennsylvania Smell Identification Test. Mean score was lower in cases than in control subjects (29.0 ± 6.1 vs 31.9 ± 4.6, p = 0.02) and was not correlated with tremor severity or duration.

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