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Neurology 2002;59:1974-1976
© 2002 American Academy of Neurology
Brief Communications

[123I]-FP-CIT-SPECT in the early diagnosis of PD presenting as exercise-induced dystonia

Regina Katzenschlager, MD, Durval Costa, MD PhD, FRCR, Svetislav Gacinovic, MD and Andrew J. Lees, MD FRCP

From the National Hospital for Neurology and Neurosurgery (Drs. Katzenschlager and Lees), Queen Square; Reta Lila Weston Institute of Neurological Studies (Drs. Katzenschlager and Lees), Royal Free and University College London Medical School; and Department of Nuclear Medicine (Drs. Costa and Gacinovic), Middlesex Hospital, London, UK.

Address correspondence and reprint requests to Professor Andrew J. Lees, Reta Lila Weston Institute of Neurological Studies, Windeyer Building, 46 Cleveland Street, London W1T 4JF, UK; e-mail: a.lees{at}ion.ucl.ac.uk

Isolated foot dystonia following exercise is a rare manifestation of early PD. It may precede the onset of parkinsonism by years and can be clinically indistinguishable from familial exercise-induced dystonia. The authors present a patient with dystonic claudication where dopamine transporter SPECT using 123I-FP-CIT allowed early diagnosis of PD and enabled effective symptomatic treatment with a dopamine agonist.




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Reproducibility of a Standardized Quantitative Analysis Using Fixed Regions of Interest to Differentiate Movement Disorders on 123I-FP-CIT SPECT
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[Abstract] [Full Text] [PDF]


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