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Bilateral subthalamic nucleus stimulation improves health-related quality of life in PD

From the Department of Clinical and Biological Neurosciences, Joseph Fourier University, Grenoble, France.

Address correspondence and reprint requests to Dr. Paul Krack, Department of Clinical and Biological Neurosciences, Joseph Fourier University, BP 217 38043, Grenoble CEDEX 9, France; e-mail: paul.krack{at}ujf-grenoble.fr

In order to assess the impact of bilateral subthalamic nucleus (STN) stimulation in PD on quality of life, the PD Quality of Life questionnaire was assessed in 60 consecutive patients with PD before surgery and 12 months after surgery. All aspects of quality of life, including motor (+48%), systemic (+34%), emotional (+29%), and social (+63%) dimensions, significantly improved with long-term STN stimulation.

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