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Neurology 2002;59:1991-1993
© 2002 American Academy of Neurology
Brief Communications

Gabapentin in late-onset poststroke seizures

J. Alvarez-Sabín, MD, J. Montaner, MD, L. Padró, MD, C. A. Molina, MD, R. Rovira, MD, A. Codina, PhD and M. Quintana

From the Cerebrovascular Unit (Drs. Alvarez-Sabín, Montaner, and Molina, M. Quintana) and the Epilepsy Unit (Drs. Padró and Rovira), Department of Neurology, Hospital Vall d’Hebron, Barcelona, Spain.

Address correspondence and reprint requests to Dr. José Alvarez-Sabín, Unidad Cerebrovascular, Servicio de Neurología, 6a planta, Hospital General Vall d’Hebron, Pg. Vall d’Hebron 119-129, Barcelona 08035, Spain; e-mail: alsa{at}hg.vhebron.es

Stroke is a frequent cause of epileptic seizures (ES) in adults. The authors evaluated the long-term efficacy and tolerability of gabapentin (900 to 1,800 mg/day) in 71 patients with a first poststroke late ES during a mean follow-up time of 30 months. ES recurred in 18.3% of the patients and side effects were noted in 27 cases (38%), but only two (2.8%) required discontinuation or early withdrawal. Gabapentin monotherapy was useful and safe for late poststroke ES.




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P. Ryvlin, A. Montavont, and N. Nighoghossian
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Neurology, December 26, 2006; 67(12_suppl_4): S3 - S9.
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O. Camilo and L. B. Goldstein
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