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Neurology 2002;59:435-437
© 2002 American Academy of Neurology
Brief Communications

Migraine and the risk of cervical artery dissection: A case-control study

C. Tzourio, MD, PhD, L. Benslamia, MD, B. Guillon, MD, S. Aïdi, MD, M. Bertrand, MSc, K. Berthet, MD and M. G. Bousser, MD

From the Service de Neurologie (Drs. Tzourio, Benslamia, Aïdi, Berthet, and Bousser), Hôpital Lariboisière; INSERM U360 (Dr. Tzourio and M. Bertrand), Hôpital de la Salpêtrière, Paris; and Service de Neurologie (Dr. Guillon), Hôpital Laënnec, Nantes, France.

Address correspondence and reprint requests to Dr. C. Tzourio, INSERM U360, Hôpital de la Salpêtrière, 75651 Paris cedex 13, France; e-mail: tzourio{at}chups.jussieu.fr

The association between migraine and cervical artery dissection (CAD) was explored in a hospital-based case-control study. Migraine was present in 49.1% (23/47) of patients with CAD and in 21% (11/52) of patients hospitalized for a cerebral ischemic event not related to a CAD (adjusted odds ratio = 3.6; 1.5 to 8.6, p = 0.005). This result supports the hypothesis that an underlying arterial wall disease could be a predisposing condition for migraine.




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