HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Correspondence: Submit a response Correspondence: View responses Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Cappa, S. F. Articles by Miniussi, C. Search for Related Content PubMed PubMed Citation Articles by Cappa, S. F. Articles by Miniussi, C. Related Collections All Neuropsychology/Behavior TMS

The role of the left frontal lobe in action naming

rTMS evidence

From IRCCS S. Giovanni di Dio (Drs. Sandrini, Rossini, Sosta, and Miniussi), Brescia; Centro di Neuroscienze Cognitive (Dr. Cappa), Università Vita–Salute S. Raffaele, Milano; and Neurologia (Dr. Rossini), Università Campus Biomedico, Roma, Italy.

Address correspondence and reprint requests to Dr. Stefano F. Cappa, Centro di Neuroscienze Cognitive, Università Vita-Salute S. Raffaele, DIBIT Via Olgettina 58, 20132 Milano, Italy; e-mail: cappa.stefano{at}hsr.it

Background: Neuropsychological and neuroimaging studies suggest that whereas the left temporal neocortex plays a crucial role in all tasks involving lexical–semantic processing, some regions of the left prefrontal convexity are selectively recruited during verb processing.

Objective: To determine if there are different neural correlates for noun and verb processing in the human brain.

Methods: Repetitive transcranial magnetic stimulation (rTMS), 20 Hz at 90% of the motor threshold, was applied to left or right prefrontal brain during object- and action-naming tasks in nine healthy subjects.

Results: A shortening of naming latency for actions was observed only after stimulation of left prefrontal cortex.

Conclusion: The involvement of the left dorsolateral frontal cortex in action naming was demonstrated using rTMS.

This article has been cited by other articles:

				J. T. Devlin and K. E. Watkins Stimulating language: insights from TMS Brain, March 1, 2007; 130(3): 610 - 622. [Abstract] [Full Text] [PDF]

				M. Cotelli, R. Manenti, S. F. Cappa, C. Geroldi, O. Zanetti, P. M. Rossini, and C. Miniussi Effect of Transcranial Magnetic Stimulation on Action Naming in Patients With Alzheimer Disease Arch Neurol, November 1, 2006; 63(11): 1602 - 1604. [Abstract] [Full Text] [PDF]

				C. Sole-Padulles, D. Bartres-Faz, C. Junque, I. C. Clemente, J. L. Molinuevo, N. Bargallo, J. Sanchez-Aldeguer, B. Bosch, C. Falcon, and J. Valls-Sole Repetitive Transcranial Magnetic Stimulation Effects on Brain Function and Cognition among Elders with Memory Dysfunction. A Randomized Sham-Controlled Study Cereb Cortex, October 1, 2006; 16(10): 1487 - 1493. [Abstract] [Full Text] [PDF]

				S. Richter, B. Schoch, O. Kaiser, H. Groetschel, C. Hein-Kropp, M. Maschke, A. Dimitrova, E. Gizewski, W. Ziegler, H.-O. Karnath, et al. Children and Adolescents With Chronic Cerebellar Lesions Show No Clinically Relevant Signs of Aphasia or Neglect J Neurophysiol, December 1, 2005; 94(6): 4108 - 4120. [Abstract] [Full Text] [PDF]

				J.-F. Demonet, G. Thierry, and D. Cardebat Renewal of the Neurophysiology of Language: Functional Neuroimaging Physiol Rev, January 1, 2005; 85(1): 49 - 95. [Abstract] [Full Text] [PDF]

				A. Floel, C. Breitenstein, S. Knecht, S.F. Cappa, M. Sandrini, P.M. Rossini, K. Sosta, and C. Miniussi The role of the left frontal lobe in action naming: rTMS evidence Neurology, March 25, 2003; 60(6): 1052 - 1052. [Full Text] [PDF]

Correspondence: