Neurology 2002;59:932-934
© 2002 American Academy of Neurology
Brief Communications
Predictors of effective bilateral subthalamic nucleus stimulation for PD
P.D. Charles, MD,
N. Van Blercom, MD,
P. Krack, MD,
S.L. Lee, MD PhD,
J. Xie, MD,
G. Besson, MD,
A.-L. Benabid, MD PhD and
P. Pollak, MD
From the Department of Clinical and Biological Neurosciences (Drs. Charles, Van Blercom, Krack, Xie, Besson, Benabid, and Pollak), Joseph Fourier University, Grenoble, France; and Vanderbilt University Medical Center (Drs. Charles and Lee), Nashville, TN.
Address correspondence and reprint requests to Professor Pierre Pollak, MD, Department of Clinical and Biological Neurosciences, Joseph Fourier University, BP 217 38043, Grenoble CEDEX 9, France; e-mail pierre.pollak{at}ujf-grenoble.fr
To identify factors predictive of effective bilateral subthalamic nucleus (STN) stimulation for PD with severe motor complications, pre- and postoperative Unified PD Rating Scale (UPDRS) scores were analyzed in a series of 54 patients who received bilateral STN stimulation. Younger age and levodopa responsiveness predict a favorable response to bilateral STN stimulation. For individual PD symptoms, those that improve with a suprathreshold dose levodopa challenge are likely to improve with stimulation.
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Correspondence:
Read all Correspondence
- Predictors of effective bilateral subthalamic nucleus stimulation for PD
- Erwin B Montgomery
- Neurology Online, 29 Oct 2002
[Full text]
- Reply to Letter to the Editor
- P Pollak, et al.
- Neurology Online, 29 Oct 2002
[Full text]
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