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Postexercise facilitation of reflexes is not common in Lambert–Eaton myasthenic syndrome

From the Department of Neurology, The Veterans Affairs Medical Center, The University of Alabama at Birmingham.

Address correspondence and reprint requests to Dr. Shin J. Oh, Department of Neurology, The University of Alabama at Birmingham, UAB Station, Birmingham, AL 34294; e-mail: shinjoh{at}uab.edu

Postexercise facilitation (PEF) with clinical reflexes, H-reflex, and T-reflexes at the ankle and knee was systematically studied in 16 patients with Lambert–Eaton myasthenic syndrome (LEMS). PEF was observed in ankle and knee deep tendon reflexes in five patients, in H-reflex in three patients, and in T-reflexes in six patients. When all reflex tests were combined, 7 (43.7%) of 16 patients showed PEF by at least one test. The authors conclude that the PEF of reflexes, the most helpful diagnostic clinical marker for LEMS, is not common.