|
|
||||||||
From the Neuroimaging Research Unit (Drs. Rovaris, Codella, and Filippi) and Clinical Trials Unit (Drs. Moiola and Comi), Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Milan; Multiple Sclerosis Center (Drs. Ghezzi and Zaffaroni), Ospedale di Gallarate; and Department of Neurological Sciences (Drs. Mancardi, Capello, and Sardanelli), University of Genoa, Italy.
Address correspondence and reprint requests to Dr. Massimo Filippi, Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, via Olgettina 60, 20132 Milan, Italy; e-mail: filippi.massimo{at}hsr.it
This baseline-vs-treatment study of 20 patients with relapsing-remitting MS investigated whether glatiramer acetate (GA) has a graduated effect on MS inflammatory activity, which was measured using monthly, standard, and triple dose gadolinium (Gd)-enhanced MRI. GA significantly reduced the mean numbers of enhancing lesions/patient/month on both standard dose and triple dose scans, without interactions with the Gd dose. GA is effective in reducing MS activity, independent of the severity of the MRI-detectable inflammatory process.
This article has been cited by other articles:
![]() |
Y. Zhao, A. Traboulsee, A. J. Petkau, and D. Li Regression of new gadolinium enhancing lesion activity in relapsing-remitting multiple sclerosis Neurology, March 25, 2008; 70(13_Part_2): 1092 - 1097. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. P. Lisak Neurodegeneration in multiple sclerosis: Defining the problem Neurology, May 29, 2007; 68(22_suppl_3): S5 - S12. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Horani, N. Muhanna, O. Pappo, A. Melhem, C. E. Alvarez, S. Doron, W. Wehbi, K. Dimitrios, S. L. Friedman, and R. Safadi Beneficial effect of glatiramer acetate (Copaxone) on immune modulation of experimental hepatic fibrosis Am J Physiol Gastrointest Liver Physiol, February 1, 2007; 292(2): G628 - G638. [Abstract] [Full Text] [PDF] |
||||
![]() |
M P Sormani, P Bruzzi, G Comi, and M Filippi The distribution of the magnetic resonance imaging response to glatiramer acetate in multiple sclerosis Multiple Sclerosis, August 1, 2005; 11(4): 447 - 449. [Abstract] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |