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Neurology 2002;59:1432-1435
© 2002 American Academy of Neurology
Brief Communications

Postictal psychosis after temporal lobectomy

C. Christodoulou, MD, M. Koutroumanidis, MD, M.J. Hennessy, MD, R.D.C. Elwes, MD, C.E. Polkey, MD and B.K. Toone, MD

From the Departments of Psychological Medicine (Drs. Christodoulou and Toone), Neurology (Drs. Koutroumanidis, Hennessy, and Elwes), and Neurosurgery (Dr. Polkey), King’s College Hospital, London, UK.

Address correspondence and reprint requests to Dr. Michael Koutroumanidis, Academic Neuroscience Centre, GKT School of Medicine, King’s Denmark Hill Campus, London, SE5 9RS, UK; e-mail: m.koutroumanidis{at}iop.kcl.ac.uk

Three of 282 consecutive patients who had temporal resections for intractable epilepsy developed postoperative postictal psychosis. These three patients had seizure recurrence contralateral to the resection, whereas none of the patients with ipsilateral seizure recurrence developed any psychiatric symptoms after surgery. Two had left amygdalo-hippocampectomy and one right temporal lobectomy. The de novo occurrence of postoperative postictal psychosis is a well-defined complication of surgery for temporal lobe epilepsy, and may relate to contralateral epileptogenesis.




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