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Neurology 2003;60:115-117
© 2003 American Academy of Neurology
Brief Communications

Preservation of branchimotor neurons of the nucleus ambiguus in multiple system atrophy

Eduardo E. Benarroch, MD DSci, Ann M. Schmeichel, AS and Joseph E. Parisi, MD

From the Department of Neurology, Mayo Clinic, Rochester, MN.

Address correspondence and reprint requests to Dr. Eduardo E. Benarroch, Department of Neurology, Mayo Clinic, 811 Guggenheim Building, 200 First Street SW, Rochester, MN 55905; e-mail: benarroch.eduardo{at}mayo.edu

Cholinergic neurons in the nucleus ambiguus (NA) were counted in autopsy tissue obtained from five patients with multiple system atrophy (MSA), four patients with PD, and five controls. The number of neurons in the dorsal NA was not significantly different among the three groups. Neurons in the ventrolateral portion of the NA were depleted in MSA. Laryngeal stridor cannot be explained solely by neuronal loss in the NA.




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E. E. Benarroch, A. M. Schmeichel, P. Sandroni, P. A. Low, and J. E. Parisi
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