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Neurology 2003;60:120-121
© 2003 American Academy of Neurology
Brief Communications

Treatment of sporadic hemiplegic migraine with calcium-channel blocker verapamil

Wengui Yu, MD PhD and Steven H. Horowitz, MD

From the Division of Neurology, University of Missouri–Columbia.

Address correspondence and reprint requests to Dr. Wengui Yu, Neurovascular Service, Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, Box 0114, San Francisco, CA 94143; e-mail: wyu_1998{at}yahoo.com

Gene mutations within the P/Q type neuronal calcium channel in familial hemiplegic migraine (FHM) suggest a therapeutic role for calcium-channel blockade. The authors have previously reported abortive therapy of FHM with IV verapamil. Here the authors describe four cases of sporadic hemiplegic migraine (SHM) responsive to verapamil, administered either orally or IV. The findings indicate that verapamil is effective therapy for both SHM and FHM.




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A. C. Lastimosa, W. Yu, and S. H. Horowitz
Treatment of sporadic hemiplegic migraine with calcium-channel blocker verapamil
Neurology, September 9, 2003; 61(5): 721 - 722.
[Full Text] [PDF]

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Treatment of sporadic hemiplegic migraine with calcium-channel blocker verapamil
Augusto Cezar Lastimosa
Neurology Online, 5 Mar 2003 [Full text]
Reply to Letter to the Editor
Wengui Yu
Neurology Online, 5 Mar 2003 [Full text]

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