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This Article Full Text Full Text (PDF) CME: Take the course for this article: Volume 60, Number 10, May 27, 2003 Correspondence: Submit a response Correspondence: View responses Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Abele, M. Articles by Klockgether, T. Search for Related Content PubMed PubMed Citation Articles by Abele, M. Articles by Klockgether, T. Related Collections Autoimmune diseases Encephalitis Gastrointestinal Gait disorders/ataxia

Prevalence of antigliadin antibodies in ataxia patients

From the Departments of Neurology (Drs. Abele and Klockgether) and Pediatrics (S. Schwartz), University of Bonn, Germany; and Department of Neurology (Dr. Schöls), St. Josef Hospital, Bochum, Germany.

Address correspondence and reprint requests to Dr. T. Klockgether, MD, Department of Neurology, University of Bonn, Sigmund-Freud-Str. 25, D-53105 Bonn, Germany; e-mail: klockgether{at}uni-bonn.de

We determined antigliadin antibodies in 95 ataxia patients and 73 controls. Antibodies were positive in 8% of the controls, 19% of patients with sporadic ataxia, 8% of patients with recessive ataxia, and 15% of patients with dominant ataxia. Statistical comparison using ² statistics did not reveal significant differences between the groups. Although we found a trend toward a higher prevalence of antigliadin antibodies in patients with sporadic ataxia and dominant ataxia, our data do not support an association of ataxia with antigliadin antibodies.

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