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Neurology 2003;60:1682-1683
© 2003 American Academy of Neurology
Brief Communications

Rates and predictors for relapse in medication overuse headache: A 1-year prospective study

Z. Katsarava, V. Limmroth, M. Finke, H. C. Diener and G. Fritsche

From the Department of Neurology, University Hospital Essen, Germany.

Address correspondence and reprint requests to Dr. Volker Limmroth, Department of Neurology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany; e-mail: volker.limmroth{at}uni-essen.de

The authors prospectively studied 98 patients with medication overuse headache. The 1-year relapse rate was 38% but was lower for patients with migraine compared with tension-type headache (22% vs 73%, p <= 0.002) and combination of migraine and tension-type headache (22% vs 77%, p <= 0.0001). The rate was also lower for patients overusing triptans than ergots (19% vs 20%, NS) and analgesics (19% vs 58%, p <= 0.001). The long-term success of withdrawal depends on the type of primary headache and the type of overused medication.


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