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Neurology 2003;60:1976-1978
© 2003 American Academy of Neurology
Brief Communications

Intrathecal baclofen for stiff-person syndrome: Life-threatening intermittent catheter leakage

J. Bardutzky, MD, V. Tronnier, MD, S. Schwab, MD and H. -M. Meinck, MD

From the Departments of Neurology (Drs. Bardutzky, Schwab, and Meinck) and Neurosurgery (Dr. Tronnier), University of Heidelberg, Germany.

Address correspondence and reprint requests to Dr. Jürgen Bardutzky, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, D-69120 Heidelberg, Germany; e-mail: juergen_bardutzky{at}med.uni-heidelberg.de

Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS). The authors report a patient with SPS who developed acute and life-threatening baclofen withdrawal symptoms. Open surgery disclosed a small position-dependent leak in the catheter connector. This catheter failure was not detected by standard noninvasive checking methods.






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