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Neurology 2003;60:870-873
© 2003 American Academy of Neurology
Brief Communications

Unilateral absence of the basal ganglia plus epilepsy without motor symptoms

C. Kellinghaus, MD, E. Montgomery, MD, S. Neme, MD, P. Ruggieri, MD and H. O. Lüders, MD PhD

From the Departments of Neurology (Drs. Kellinghaus, Montgomery, Neme, and Lüders) and Radiology (Dr. Ruggieri), The Cleveland Clinic Foundation, OH.

Address correspondence to Dr. Christoph Kellinghaus, Department of Neurology, Desk S51, 9500 Euclid Ave., Cleveland, OH 44195; e-mail: kellingc{at}ccf.org

A patient with absence of the basal ganglia and refractory epilepsy without impairment of pyramidal or extrapyramidal motor function is reported. Imaging findings suggest a vascular insult as etiology. Preserved motor function could be explained by neuronal plasticity involving contralateral corticostriatal and pallidothalamic connections and points to a lesion received in early pregnancy.






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