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Neurology 2003;60:1534-1536
© 2003 American Academy of Neurology
Brief Communications

Hypertensive encephalopathy

Antecedent to hippocampal sclerosis and temporal lobe epilepsy? C. Solinas, MD, R. S. Briellmann, MD, A. S. Harvey, MD, L. A. Mitchell, FRACR and S. F. Berkovic, MD

From the Epilepsy Research Institute (Drs. Solinas, Briellmann, Harvey, and Berkovic) and Departments of Medicine (Neurology) (Drs. Briellmann and Berkovic) and Radiology (Dr. Mitchell), University of Melbourne and Austin and Repatriation Medical Center; and Department of Neurology (Dr. Harvey), Royal Children’s Hospital, Melbourne, Victoria, Australia.

Address correspondence and reprint requests to Prof. Samuel F. Berkovic, Epilepsy Research Institute, Neurosciences Building, Repatriation Campus, Heidelberg, Victoria 3081, Australia; e-mail: s.berkovic{at}unimelb.edu.au

The authors describe three patients with refractory temporal lobe epilepsy (TLE) following an episode of hypertensive encephalopathy as their only identified antecedent event. All patients had typical MR features of hippocampal sclerosis (HS), and the two operated cases had typical HS histology and became seizure-free postoperatively. These cases suggest that hypertensive encephalopathy may be a rare form of initial precipitating injury, leading to TLE and HS.




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Correspondence:

Read all Correspondence

Hypertensive encephalopathy: Antecedent to hippocampal sclerosis and temporal lobe epilepsy?
Gregory Y Chang
Neurology Online, 19 Jun 2003 [Full text]
Reply to Chang
Regula Briellmann, et al.
Neurology Online, 19 Jun 2003 [Full text]