Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Data Supplement
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rostasy, K.
Right arrow Articles by Hanefeld, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rostasy, K.
Right arrow Articles by Hanefeld, F.
Related Collections
Right arrow All Immunology
Right arrow All Infections
Right arrow Bacterial infections
Right arrow Multiple sclerosis

Neurology 2003;61:125-128
© 2003 American Academy of Neurology
Brief Communications

Chlamydia pneumoniae in children with MS

Frequency and quantity of intrathecal antibodies

K. Rostasy, MD, H. Reiber, PhD, D. Pohl, MD, P. Lange, BSc, A. Ohlenbusch, PhD, H. Eiffert, MD, M. Maass, MD and F. Hanefeld, MD

From the Department of Pediatric Neurology (Drs. Rostasy, Pohl, Ohlenbusch, and Hanefeld), Neurochemistry Laboratory (Drs. Reiber and Lange), and Department of Bacteriology (Dr. Eiffert), University of Göttingen; and Institute of Medical Microbiology and Hygiene (Dr. Maass), University of Lübeck, Germany.

Address correspondence and reprint requests to Kevin Rostasy, Pediatric Neurology, Georg-August-University of Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany; e-mail: Krostasy{at}excite.com

The authors investigated the frequency and quantity of intrathecal antibody synthesis against Chlamydia pneumoniae and the presence of C pneumoniae antigen in 25 children with MS. C pneumoniae genome was present in two children. In seven children an intrathecal synthesis of C pneumoniae antibodies was detected, representing only a small part of the total intrathecal immunoglobulin G, suggesting that this intrathecal synthesis is part of a polyspecific, oligoclonal immune response.




This article has been cited by other articles:


Home page
 NeurologyHome page
J. M. Ness, D. Chabas, A. D. Sadovnick, D. Pohl, B. Banwell, B. Weinstock-Guttman, and for the International Pediatric MS Study Group
Clinical features of children and adolescents with multiple sclerosis
Neurology, April 17, 2007; 68(16_suppl_2): S37 - S45.
[Abstract] [Full Text] [PDF]

Home page
 Mult SclerHome page
P G Bagos, G Nikolopoulos, and A Ioannidis
Chlamydia pneumoniae infection and the risk of multiple sclerosis: a meta-analysis
Multiple Sclerosis, August 1, 2006; 12(4): 397 - 411.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
M. S. Freedman, E. J. Thompson, F. Deisenhammer, G. Giovannoni, G. Grimsley, G. Keir, S. Ohman, M. K. Racke, M. Sharief, C. J. M. Sindic, et al.
Recommended Standard of Cerebrospinal Fluid Analysis in the Diagnosis of Multiple Sclerosis: A Consensus Statement
Arch Neurol, June 1, 2005; 62(6): 865 - 870.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2003 by AAN Enterprises, Inc.