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This Article Full Text Full Text (PDF) CME: Take the course for this article: Volume 61, Number 3, August 12, 2003 Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Lin, J.-H. Articles by Liu, C.-K. Search for Related Content PubMed PubMed Citation Articles by Lin, J.-H. Articles by Liu, C.-K. Related Collections All Cerebrovascular disease/Stroke Infarction All Cognitive Disorders/Dementia Vascular dementia

Prediction of poststroke dementia

From the School of Physical Therapy (Drs. J.-H. Lin and Hsiao), College of Health Science, and Department of Neurology (Drs. R.-T. Lin, Tai, and Liu), Kaohsiung Medical University Hospital and Graduate Institute of Behaviour Science, Kaohsiung Medical University, and School of Occupational Therapy (Dr. Hsieh), College of Medicine, National Taiwan University, Taiwan.

Address correspondence and reprint requests to Dr. C.-K. Liu, Department of Neurology, Kaohsiung Medical University Hospital, No. 100, Shih-Chuan, 1st Road, Kaohsiung 807, Taiwan, ROC; e-mail: ckliu{at}kmu.edu.tw

Objective: To investigate prospectively the frequency and clinical determinants of poststroke dementia (PSD) in a cohort of consecutive ischemic stroke inpatients in southern Taiwan.

Methods: A standard stroke evaluation protocol was conducted at admission and 3 months after an ischemic stroke. The protocol included clinical, neurologic, neurobehavioral, and functional assessments as well as neuroimaging examinations. Diagnoses were made according to the Neurologic Adaptation of the 10th edition of the International Classification of Diseases criteria for dementia.

Results: Excluding patients with prestroke dementia, a total of 283 patients were surveyed at 3 months after stroke; 26 (9.2%) of them met the criteria for PSD. The correlates of PSD in logistic regression analyses were age 65 years or older (odds ratio [OR] 6.6) vs <65 years, previous occupation as a laborer (OR 3.3), prior stroke (OR 3.1), left carotid vascular territory (OR 12.5) vs vertebrobasilar and unknown territories, moderate to severe stroke severity (OR 3.4), and cognitive impairment (OR 4.5) and poorer functional status at admission (OR 4.5). Based on the significant predictors identified, the logistic regression model correctly classified PSD in 93.4% of subjects.

Conclusion: The lower frequency of PSD in this study from Taiwan compared with previous studies from Western countries may have been due to the relatively younger age of the elderly population and the use of stricter diagnostic criteria.

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