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Neurology 2003;61:829-831
© 2003 American Academy of Neurology
Brief Communications

Progressive myoclonus in a child with a deep cerebellar mass

Jonathan W. Mink, MD PhD, Paul A. Caruso, MD and Scott L. Pomeroy, MD PhD

From the University of Rochester School of Medicine and Golisano Children’s Hospital at Strong (Dr. Mink), Rochester, NY; Department of Radiology (Dr. Caruso), Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston; and Department of Neurology (Dr. Pomeroy), Children’s Hospital, Harvard Medical School, Boston, MA.

Address correspondence and reprint requests to Dr. Jonathan W. Mink, Child Neurology, Box 631, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY 14642; e-mail: Jonathan_Mink{at}urmc.rochester.edu

Myoclonus is often associated with pathology of the cerebellum. However, the site of neurons responsible for the generation of myoclonus in cerebellar disease is not known. The authors report a young child with myoclonus associated with a ganglioglioma in the region of the deep cerebellar white matter and cerebellar nuclei. They hypothesize that abnormal paroxysmal discharge of neurons in the cerebellar nuclei can generate myoclonus.




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Correspondence:

Read all Correspondence

Progressive myoclonus in a child with a deep cerebellar mass
Taranath Shetty
Neurology Online, 16 Dec 2003 [Full text]
Reply to Shetty and Gilbert
Jonathan W. Mink
Neurology Online, 16 Dec 2003 [Full text]
Progressive myoclonus in a child with a deep cerebellar mass
Gordon J Gilbert, MD, PA
Neurology Online, 16 Dec 2003 [Full text]