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 Volume 61, Number 6, September 23, 2003
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Neurology 2003;61:831-833
© 2003 American Academy of Neurology
Brief Communications

Prognosis of patients with suspected primary CNS angiitis and negative brain biopsy

Abdulrahman A. Alreshaid, MD and William J. Powers, MD

From the Departments of Neurology, Neurological Surgery, and Radiology, Washington University School of Medicine, St. Louis, MO.

Address correspondence and reprint requests to Dr. W.J. Powers, East Building Imaging Center, Campus Box 8225, Washington University School of Medicine, 4525 Scott Ave., St. Louis, MO 63110; e-mail: wjp{at}.npg.wustl.edu

The authors retrospectively analyzed 25 patients who had a nondiagnostic brain biopsy for clinically suspected primary CNS angiitis to determine the effect of immunosuppressive therapy on 1-year outcome. Good outcome was seen in 6 of 10 treated patients and in 8 of 15 untreated patients (p= 0.93). These findings do not indicate that the addition of immunosuppressive therapy significantly enhances outcome of patients with clinically suspected primary angiitis of the CNS and a nondiagnostic brain biopsy.




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Y. Kadkhodayan, A. Alreshaid, C. J. Moran, D. T. Cross III, W. J. Powers, and C. P. Derdeyn
Primary Angiitis of the Central Nervous System at Conventional Angiography
Radiology, December 1, 2004; 233(3): 878 - 882.
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