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Neurology 2003;61:834-836
© 2003 American Academy of Neurology


Brief Communications

Amyloidoma of a spinal root

S. McKechnie, FRACS, F. Yang, MMed, C. G. Harper, MD FRCPA, M. McGee–Collett, FRACS, C. J.A. Henderson, FRCPA, J. J. Liepnieks, PhD, M. Yazaki, PhD, M. D. Benson, MD and J. G. McLeod, MBBS DSc

From the Department of Neurosurgery (Dr. McKechnie) and Southwestern Area Pathology Service (Dr. Henderson), Liverpool Hospital, and Institute of Clinical Neurosciences (Drs. Yang, Harper, McGee–Collett, and McLeod), Royal Prince Alfred Hospital and University of Sydney, New South Wales, Australia; and Department of Pathology and Laboratory Medicine (Drs. Liepnieks, Yazaki, and Benson), Indiana University School of Medicine, Indianapolis.

Address correspondence and reprint requests to Dr. J.G. McLeod, Department of Medicine, University of Sydney, NSW 2006, Australia; e-mail: jmcl7953{at}mail.usyd.edu.au

A unique case of amyloidoma presenting as a dumbbell-shaped tumor of a spinal root without bony erosion is described. Amyloid was also present in the facial nerve. DNA analysis for transthyretin was negative. Isolated amyloid fibers contained lambda light chains, and although plasma and urine immunoelectrophoresis performed by immunofixation was normal, it is possible the tumor may have been derived from an isolated plasmacytoma.







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