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Glucose levels and outcome after subarachnoid hemorrhage

From the Department of Neurology (Drs. Dorhout Mees, van Dijk, Algra, and Rinkel, D.R.J. Kempink), Rudolf Magnus Institute of Neuroscience, and Julius Center for Health Sciences and Primary Care (Dr. Algra), University Medical Center Utrecht, the Netherlands.

Address correspondence and reprint requests to Dr. G.W. van Dijk, Department of Neurology, University Medical Center Utrecht, PO Box 85500, 3584 CX Utrecht, the Netherlands; e-mail: g.w.dijk{at}neuro.azu.nl

Abstract– In a cohort of 337 patients with subarachnoid hemorrhage (SAH), we investigated the relationship between blood glucose levels, baseline characteristics, and outcome by means of Student’s t-test and multivariate logistic regression. The mean glucose levels on admission and from day 1 to 10 were significantly higher in patients with poor condition on admission and in patients with poor outcome. In a multivariate analysis, glucose level on admission was not an independent predictor of outcome. Hyperglycemia may be a link in the association between poor condition on admission and poor outcome.

Received March 17, 2003. Accepted in final form June 18, 2003.

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