Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kadhim, H.
Right arrow Articles by Sébire, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kadhim, H.
Right arrow Articles by Sébire, G.
Related Collections
Right arrow All Immunology
Right arrow All Pediatric
Right arrow Neonatal
NEUROLOGY 2003;61:1256-1259
© 2003 American Academy of Neurology
Brief Communications

Distinct cytokine profile in SIDS brain

A common denominator in a multifactorial syndrome?

Hazim Kadhim, MD PhD, André Kahn, MD PhD and Guillaume Sébire, MD PhD

From the Laboratoire de Neurologie du Développement (Drs. Kadhim and Sébire), Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels; Unité de Neuropathologie, Service d’Anatomopathologie, CHU Brugmann-HUDERF (Dr. Kadhim), and Service de Pédiatrie, Hôpital Universitaire des Enfants Reine Fabiola HUDERF (Drs. Kadhim and Kahn), Université Libre de Bruxelles (ULB), Belgium; and Service de Neurologie Pédiatrique (Dr. Sébire), CHU Fleurimont, Université de Sherbrooke, Canada.

Address correspondence and reprint requests to Dr. Hazim Kadhim, Laboratoire de Neurologie du Développement (NEPE), Université Catholique de Louvain (UCL), Avenue Mounier 52, Tour Vésale, NEPE, 1200 Brussels, Belgium; e-mail: Hazim.Kadhim{at}nepe.ucl.ac.be

Cytokines modify neuronal function. Dysfunction in vital centers is reported in sudden infant death syndrome (SIDS). The authors detected high neuronal interleukin (IL)-1ß immunoreactivity in the arcuate and dorsal vagal nuclei in SIDS. This IL-1 overexpression might contribute to molecular interactions in brainstem neurovegetative centers, causing disturbed homeostatic control of cardiorespiratory and arousal responses, possibly leading to SIDS.

Received November 4, 2002. Accepted in final form July 22, 2003.

See also page 1170




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
B. T. Thach
Some aspects of clinical relevance in the maturation of respiratory control in infants
J Appl Physiol, June 1, 2008; 104(6): 1828 - 1834.
[Abstract] [Full Text] [PDF]

Home page
 CMAJHome page
C. E. Hunt and F. R. Hauck
Sudden infant death syndrome.
Can. Med. Assoc. J., June 20, 2006; 174(13): 1861 - 1869.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child.Home page
C E Hunt
Gene-environment interactions: implications for sudden unexpected deaths in infancy
Arch. Dis. Child., January 1, 2005; 90(1): 48 - 53.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
H. F. Krous, R. W. Byard, and T. O. Rognum
Pathology Research Into Sudden Infant Death Syndrome: Where Do We Go From Here?
Pediatrics, August 1, 2004; 114(2): 492 - 494.
[Full Text] [PDF]

Home page
 NeurologyHome page
B. T. Thach
The brainstem and vulnerability to sudden infant death syndrome
Neurology, November 11, 2003; 61(9): 1170 - 1171.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2003 by AAN Enterprises, Inc.