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From the Departments of Medicine (Drs. Hummers, Rosen, Mahoney, and Wigley, S. Morris), Neurology (Dr. Kerr, C. Krishnan), Dermatology (Dr. CasciolaRosen), and Cell Biology and Anatomy (Dr. Rosen), Johns Hopkins University, Baltimore, MD.
Address correspondence and reprint requests to Dr. L.K. Hummers, Department of Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, 1B.46, Baltimore, MD 21224; e-mail: lhummers{at}jhmi.edu
Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord. The authors observed cases of recurrent TM in patients where anti-Ro (SSA) antibodies were present and therefore performed a case-control study to examine the frequency of anti-Ro autoantibodies in patients with recurrent TM and control subjects. Antibodies to 52-kd Ro were demonstrated in 77% of cases (10/13) compared with only 33% of control subjects (4/12).
Received May 15, 2003. Accepted in final form September 11, 2003.
Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the January 13 issue to find the title link for this article.
Drs. Hummers, Kerr, and Wigley and C. Krishnan contributed equally to this manuscript.
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