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NEUROLOGY 2004;62:2088-2091
© 2004 American Academy of Neurology
Brief Communications

Perinatal stroke in term infants with neonatal encephalopathy

V. Ramaswamy, BSc, S. P. Miller, MD, A. J. Barkovich, MD, J. C. Partridge, MD MPH and D. M. Ferriero, MD

From the Departments of Neurology (V. Ramaswamy, and Drs. Miller, Barkovich, and Ferriero), Pediatrics (Drs. Miller, Barkovich, Partridge, and Ferriero), and Radiology (Dr. Barkovich), University of California San Francisco.

Address correspondence and reprint requests to Dr. Donna M. Ferriero, Department of Neurology, University of California, 521 Parnassus Ave., San Francisco, CA 94143–0663; e-mail: dmf{at}itsa.ucsf.edu

In a prospective cohort of 124 encephalopathic term infants, six infants had an acute focal stroke. All six encephalopathic patients with strokes presented with seizures. Neurodevelopmental outcome at 30 months was abnormal in all six patients and significantly worse when compared with the entire cohort overall. These findings suggest that in newborns with encephalopathy, acute focal strokes are an uncommon but serious occurrence with substantial risk for abnormal neurodevelopmental outcome.

Received December 12, 2003. Accepted in final form February 18, 2004.




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Correspondence:

Read all Correspondence

Perinatal stroke in term infants with neonatal encephalopathy
Frances M Cowan, et al.
Neurology Online, 31 Aug 2004 [Full text]
Reply to Cowan et al
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