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From the Roy J. and Lucille A. Carver College of Medicine Sleep Disorders Center (Drs. Dyken and Yamada, C. Glenn) and the Departments of Neurology and Internal Medicine (Dr. Berger), University of Iowa, Iowa City, IA.
Address correspondence and reprint requests to Dr. M.E. Dyken, Department of Neurology, University of Iowa, Iowa City, IA 52242; e-mail: mark-dyken{at}uiowa.edu
An increase in the arousal threshold may predispose critically ill patients with obstructive sleep apnea (OSA) to prolonged apneas and death during sleep. We report two cases in whom polysomnographically documented OSA resulted in EEG changes compatible with cerebral hypoxemia with subsequent respective transient encephalopathy in one instance and death in the other.
Received August 7, 2003. Accepted in final form October 6, 2003.
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