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NEUROLOGY 2004;62:806-808
© 2004 American Academy of Neurology
Brief Communications

MRI criteria for multiple sclerosis

Evaluation in a pediatric cohort

Cecil D. Hahn, MD, Manohar M. Shroff, MD, Susan I. Blaser, MD and Brenda L. Banwell, MD

From the Division of Neurology (Drs. Hahn and Banwell) and Department of Diagnostic Imaging (Drs. Shroff and Blaser), The Hospital for Sick Children and University of Toronto, Ontario, Canada.

Address correspondence and reprint requests to Dr. Brenda L. Banwell, Division of Neurology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada; e-mail: brenda.banwell{at}sickkids.ca

This study assessed the validity of established MRI criteria for multiple sclerosis (MS) in a cohort of 20 children with clinically definite MS. The authors found that many pediatric MS patients did not meet the MRI criteria established for adult-onset MS, particularly the McDonald MRI criteria for dissemination in space. The authors thus suggest that MRI criteria for adult MS be applied cautiously to pediatric MS patients.

Received April 16, 2003. Accepted in final form October 29, 2003.




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