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NEUROLOGY 2004;62:978-980
© 2004 American Academy of Neurology
Brief Communications

Devic disease and thymoma with anti-central nervous system and antithymus antibodies

J. -C. Antoine, MD PhD, J. -P. Camdessanché, MD, L. Absi, PhD, F. Lassablière and L. Féasson, MD

From the Service de Neurologie and EA 3062 (Drs. Antoine and Camdessanché, F. Lassablière), Etablissement Français du Sang and EA 3062 (Dr. Absi), and Service de Physiologie et Médecine du Sport and EA 3062 (Dr. Féasson), Faculté de Médecine de Saint-Etienne, France.

Address correspondence and reprint requests to Dr. Jean-Christophe Antoine, Service de Neurologie, Hôpital de Bellevue, 42055 Saint-Etienne Cedex 02, France; e-mail: j.christophe.antoine{at}chu-st-etienne.fr

A patient with myasthenia gravis and thymoma developed neuromyelitis optica (NMO) and necrotizing myositis 4 months after treatment of the tumor. Antibodies reacting with the CNS and thymic epithelial cells were detected in the serum during the acute phase of NMO, suggesting that the NMO was linked to the thymoma.

Received September 9, 2003. Accepted in final form November 26, 2003.




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