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NEUROLOGY 2004;62:1202-1205
© 2004 American Academy of Neurology
Brief Communications

Retinal vascular abnormalities in CADASIL

C. Haritoglou, MD, G. Rudolph, MD, J. P. Hoops, MD, C. Opherk, MD, A. Kampik, MD and M. Dichgans, MD

From the Departments of Ophthalmology (Drs. Haritoglou, Rudolph, Hoops, and Kampik) and Neurology, Klinikum Großhadern (Drs. Opherk and Dichgans), Ludwig-Maximilians-University, Munich, Germany.

Address correspondence and reprint requests to Dr. Martin Dichgans, Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians-University, Marchioninistrasse 15, D 81377-Munich, Germany; e-mail: mdichgans{at}nefo.med.uni-muenchen.de

To assess retinal vascular alterations in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, the authors examined 10 affected individuals with ophthalmologic evaluation including fluorescence angiography. Findings included bilateral peripapillary arteriolar sheathing (30%), arteriolar narrowing (80%), and arteriovenous nicking (90%). No retinal infarcts, vascular occlusions, exudation, or hypoperfusion of affected vessels were found.

Received June 25, 2003. Accepted in final form October 6, 2003.




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