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NEUROLOGY 2004;62:1408-1410
© 2004 American Academy of Neurology
Brief Communications

Myoclonic status epilepticus following repeated oral ingestion of colloidal silver

S. M. Mirsattari, MD FRCPC, R. R. Hammond, MD FRCPC, M. D. Sharpe, MD FRCPC, F. Y. Leung, PhD and G. B. Young, MD FRCPC

From the Departments of Clinical Neurological Sciences (Drs. Mirsattari and Young), Pathology (Dr. Hammond), Biochemistry (Dr. Leung), and Anesthesia and Perioperative Medicine (Dr. Sharpe), University of Western Ontario, London, Ontario, Canada.

Address correspondence and reprint requests to Dr. G. Bryan Young, Room 10-OF9, Department of Clinical Neurological Sciences, London Health Sciences Centre, 339 Windermere Road, London, Ontario, Canada N6A 5A5; e-mail: Bryan.Young{at}lhsc.on.ca

The authors report a case of a 71-year-old man who developed myoclonic status epilepticus and coma after daily ingestion of colloidal silver for 4 months resulting in high levels of silver in plasma, erythrocytes, and CSF. Despite plasmapheresis, he remained in a persistent vegetative state until his death 5.5 months later. Silver products can cause irreversible neurologic toxicity associated with poor outcome.

Received August 5, 2003. Accepted in final form December 19, 2003.




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K. M Stepien, R. Morris, S. Brown, A. Taylor, and L. Morgan
Unintentional silver intoxication following self-medication: an unusual case of corticobasal degeneration
Ann Clin Biochem, November 1, 2009; 46(6): 520 - 522.
[Abstract] [Full Text] [PDF]


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