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Ropinirole in Gilles de la Tourette syndrome

From the Department of Neurology, Tel-Aviv Medical Center, and the Sieratzki Chair of Neurology, Sackler Faculty of Medicine, Tel-Aviv University, Israel.

Address correspondence and reprint requests to Dr. A.D. Korczyn, Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv 69978, Israel; e-mail: neuro13{at}post.tau.ac.il

The effects of treatment with ropinirole (0.25 to 0.5 mg bid) were examined using an open-label design for 8 weeks in 15 subjects with Gilles de la Tourette syndrome (GdlT). All patients completed the study, and most showed an improvement in their tics during treatment. Low-dose ropinirole may improve the motor features in GdlT, but further controlled studies are necessary.

Received April 2, 2002. Accepted in final form December 30, 2003.

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