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NEUROLOGY 2004;63:1942-1943
© 2004 American Academy of Neurology
Brief Communications

Single-fiber EMG in familial hemiplegic migraine

G. M. Terwindt, MD, PhD, E. E. Kors, MD, A. A. Vein, MD, PhD, M. D. Ferrari, MD, PhD and J. G. van Dijk, MD, PhD

From the Department of Neurology and Clinical Neurophysiology, Leiden University Medical Center, The Netherlands.

Address correspondence and reprint requests to Dr. Gisela M. Terwindt, Department of Neurology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands; e-mail: G.M.Terwindt{at}lumc.nl

Twelve familial hemiplegic migraine (FHM) patients (6 with the I1811L mutation in CACNA1A, 3 with M731T mutation in ATP1A2, and 3 without known mutations) and 10 control subjects underwent single-fiber EMG. Mean jitter did not differ significantly between patients and control subjects or among patients. No blocking was found. The results suggest that neuromuscular function is normal in FHM.

Received December 5, 2003. Accepted in final form July 9, 2004.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the November 23 issue to find the title link for this article.




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J. E. Schoenen, A. Ambrosini, A. M. de Noordhout, J. G. van Dijk, G.M. Terwindt, E.E. Kors, A.A. Vein, and M.D. Ferrari
Single-fiber EMG in familial hemiplegic migraine
Neurology, May 10, 2005; 64(9): 1666 - 1667.
[Full Text] [PDF]

Correspondence:

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Single-fiber EMG in familial hemiplegic migraine
Jean E Schoenen, et al.
Neurology Online, 21 Jan 2005 [Full text]
Reply to Shoenen et al
J. Gert van Dijk, et al.
Neurology Online, 21 Jan 2005 [Full text]

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