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NEUROLOGY 2004;63:1962-1965
© 2004 American Academy of Neurology
Brief Communications

Progressive prosopagnosia

Clinical and neuroimaging results

S. Joubert, PhD, O. Felician, MD, E. Barbeau, PhD, A. Sontheimer, MSc, E. Guedj, MD, M. Ceccaldi, MD, PhD and M. Poncet, MD, PhD

From the Service de Neurologie et de Neuropsychologie, AP-HM Timone; and Laboratoire de Neurophysiologie et Neuropsychologie, INSERM EMI-U 9926, Faculté de Médecine, Univ. Mediterranee, Marseille, France.

Address correspondence and reprint requests to Dr. Sven Joubert, Centre de recherche, Institut universitaire de gériatrie de Montréal, 4565, chemin Queen-Mary, Montreal, Quebec, H3W 1W5 Canada; e-mail: sven.joubert{at}medecine.univ-mrs.fr

The authors report the longitudinal case study of a patient with the right temporal variant of frontotemporal lobar degeneration. His deficit, initially limited to visuoperceptual disturbances, progressed 2 years later to a severe semantic breakdown. Neuroimaging data indicate that the underlying degenerative process, initially confined to unimodal visual associative cortices, progressed along the ventral pathways to multimodal areas in charge of integrating knowledge from various modalities (the anterior temporal lobes).

Received May 1, 2004. Accepted in final form July 2, 2004.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the November 23 issue to find the title link for this article.




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[Abstract] [Full Text] [PDF]


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