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Treatment of low-grade oligodendroglial tumors without radiotherapy

From the Department of Neurological Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.

Address correspondence and reprint requests to Dr. Yasuo Iwadate, Department of Neurological Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba 260-8670, Japan; e-mail: iwadatey{at}faculty.chiba-u.jp

The authors prospectively treated 18 consecutive patients with low-grade oligodendroglial tumors without postoperative radiotherapy. The treatment strategy was as follows: follow-up after total resection and chemotherapy after subtotal resection or biopsy. All patients were alive and 17 patients (94%) were progression-free after a median follow-up of 4.7 years. The results suggested that radiotherapy could be postponed until clinical progression in the treatment of low-grade oligodendroglial tumors.

Received March 22, 2004. Accepted in final form August 2, 2004.

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