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NEUROLOGY 2004;63:2393-2395
© 2004 American Academy of Neurology
Brief Communications

Physical training and fatigue, fitness, and quality of life in Guillain–Barré syndrome and CIDP

M. P.J. Garssen, MD, J. B.J. Bussmann, PhD, P. I.M. Schmitz, PhD, A. Zandbergen, MA, T. G. Welter, PhD, I. S.J. Merkies, MD, PhD, H. J. Stam, MD, PhD and P. A. van Doorn, MD, PhD

From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.

Address correspondence and reprint requests to Dr. M.P.J. Garssen, Department of Neurology, Erasmus Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, the Netherlands; e-mail: m.garssen{at}erasmusmc.nl

Many patients with Guillain–Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) experience excessive fatigue, which may persist for years and reduce quality of life. The authors performed a 12-week study of bicycle exercise training in 20 patients with severe fatigue, 16 with relatively good recovery from GBS, and 4 with stable CIDP. Training seemed well tolerated, and self-reported fatigue scores decreased 20% (p = 0.001). Physical fitness, functional outcome, and quality of life were improved.

Received May 21, 2004. Accepted in final form August 12, 2004.




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