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NEUROLOGY 2004;63:2433-2435
© 2004 American Academy of Neurology
Brief Communications

Familial aggregation of strong hemispheric language lateralization

K. Anneken, MD*, C. Konrad, MD*, B. Dräger, MD, C. Breitenstein, PhD, I. Kennerknecht, MD, E. B. Ringelstein, MD and S. Knecht, MD

From the Departments of Neurology (Drs. Anneken, Konrad, Dräger, Breitenstein, Ringelstein, and Knecht) and Psychiatry (Dr. Konrad) and Institute of Human Genetics (Dr. Kennerknecht), University of Muenster, Germany.

Address correspondence and reprint requests to Dr. K. Anneken, Department of Neurology, University of Muenster, Albert-Schweitzer-Str. 33, 48129 Muenster, Germany; e-mail: anneken{at}uni-muenster.de

The most conspicuous aspect of the neural basis of language is the uneven involvement of the cerebral hemispheres. The familial distribution of variable degrees of left-hemispheric language lateralization was investigated. A significant familial aggregation of strong left-hemispheric language lateralization and a positive association of the degree of language lateralization between parents and their children were found. These data strongly suggest a genetic determination of the degree of language lateralization.

Received November 10, 2003. Accepted in final form July 26, 2004.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the December 28 issue to find the title link for this article.

*These authors contributed equally to this work.


Related Article

December 28 Highlights
Neurology 2004 63: 2202-2003. [Full Text] [PDF]





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